Eat well. Be well.


Science Shows DHEA Works Best as Cream, Not Pill

HOUSTON, TX–(Marketwire – March 5, 2012) – Though your skin may be the most visible indicator of health and age, by age 35 there are other noticeable signs hormone levels are declining. These signs may include decreased energy, less mental clarity, dry thin skin, trouble sleeping, increased abdominal fat and reduced sex drive, among others. The right DHEA supplement provided the right way can stave off many physical and mental symptoms of declining hormones.

DHEA (Dehydroepiandrosterone) is a prohormone — a natural base building block for hormones. Levels of DHEA peak by about age 25 when we are “in our prime” and decline thereafter. After age 25 we make about 2% less per year. DHEA is a base for testosterone, estrogen, estradiol and about 50 other hormones.

Medical research shows why DHEA is best delivered to the body as a bioidentical cream absorbed in the skin, rather than as a pill supplement.

Oral DHEA ingested in pill or spray form is inactivated by the “first-pass effect” of the liver. This means that the liver filters out most DHEA before it can do any good — what does get into the bloodstream is DHEA-S (DHEA sulfate).

DHEA-S is a different pro-hormone and has different benefits than DHEA. Medical research shows DHEA is converted into DHEA-S, but not the other way around. So, DHEA-S is not converted by the body into DHEA.1

In the past, most medical research studies of “DHEA” were conducted using DHEA in pill form. As a consequence, many of these studies found only minimal benefit to “DHEA.” But with oral supplementation these studies were only testing the benefits of DHEA sulfate supplementation. These studies did not test DHEA with the proper method of use.

Further medical research shows the human body metabolizes most DHEA into other hormones in the skin (the dermis). In other words, the skin is where we process most of the DHEA we make. DHEA is also a base for skin oil, called sebum; it has also been found to help protect the skin from carcinogens and improve skin hydration.2

Get Your at-home Hormone Test Kit Here

For optimum results, DHEA must be delivered to the body properly as a bioidentical DHEA cream.

Twist25 ® DHEA Cream is scientifically formulated for maximum absorption and processing in the skin.

When rubbed into the skin, Twist 25 provides bioidentical DHEA, rather than DHEA-S. This is DHEA the right way. Twist 25 is what the body uses where the body uses it — that is why users get noticeable results within three weeks.

Twist 25 DHEA cream by Health2Go, Inc. is a premium quality bioidentical DHEA cream. See and feel results within a few weeks.

Why is Twist 25 DHEA cream the best money can buy?

  • Twist 25 was developed by John R. Woodward, MD. In private practice at Medical City in Dallas, Texas for 39 years, Dr. Woodward is a Yale graduate, Board certified Ob-Gyn specializing in bioidentical hormone replacement therapy.
  • Twist 25 has been researched, developed, tested and refined for 15 years.
  • Twist 25 is a specially compounded proprietary cream containing 50 mg/cc (5%) pharmaceutical grade bioidentical DHEA.
  • Twist 25 is tested by an independent laboratory to ensure proper mix and strength.
  • Developed by a physician, trusted by physicians and pharmacists nationwide.

Twist 25 is the best DHEA cream available. We don’t cut corners when it comes to quality. Only the best will do.

  • Safety tested
  • Twist 25 provides what the body uses where the body uses it
  • Absorbs in 10 seconds
  • Leaves no oily residue
  • Fragrance free
  • Contains Co-enzyme Q-10 and Vitamin E
  • No soy, no parabens, gluten free, no lecithin, no cyclodextrines
  • Made in the U.S.A.
  • Patent pending

It’s the little things we do each day that make the big differences.

Look your best and feel your best with Twist 25.

About Health2Go, Inc.
Health2Go, Inc. develops, manufactures and provides leading-edge, top quality anti-aging products. To learn more about Health2Go, Inc. or its anti-aging and wellness products, visit Twist 25.

1 Fabian Hammer, Sandra Subtil, Philipp Lux, Christiane Maser-Gluth, Paul M. Stewart, Bruno Allolio and Wiebke Arlt. No Evidence for Hepatic Conversion of Dehydroepiandrosterone (DHEA) Sulfate to DHEA: In Vivo and in Vitro Studies. Journal of Clinical Endocrinology and Metabolism Vol. 90, No. 6 3600-3605

2 Fernand Labrie, Alain Belanger, Rene Berube, et al. University of Toronto Medical School. The Journal of Steroid Biochemistry and Molecular Biology Vol 103, Issue 2, February 2007, Pgs 178-188

Get Yours Today 2



  • Lillian Schaeffer May 4, 2018 at 9:18 am

    I think it’s amazing that Twist 25 DHEA cream has been tested for 15 years. That’s a really long time to be testing a product, and that fills me with confidence that it’s effective. My husband has been talking about getting DHEA supplements, but maybe I could recommend this kind of cream to him instead.


Leave a Comment