Do you know the DHEA hormone connection with coronary heart disease?
Do you know the connection between low DHEA levels and coronary heart disease?
A study published in the Journal of the American College of Cardiology took a look at this connection.
The adrenal sex hormone dehydroepiandrosterone (DHEA), which is present in serum mainly as the sulfate DHEA-S, is the most abundant steroid hormone in human blood.
Its levels decline dramatically with age, beginning around age 30 years.
This study tested the hypothesis that serum DHEA and DHEA-S are predictors of major coronary heart disease (CHD) and/or cerebrovascular disease (CBD) events in a large cohort of elderly men.
This study concluded, “Low serum levels of DHEA and its sulfate predict an increased risk of CHD, but not CBD, events in elderly men.”
In fact the the association between DHEA and coronary heart disease risk remained significant after adjustment for traditional cardiovascular risk factors, serum total testosterone and estradiol, C-reactive protein.
This study lasted five years and involved 302 participants who had a CHD event.
“Low serum levels of DHEA and its sulfate predict an increased risk of CHD, but not CBD, events in elderly men,” concluded the researchers.
Topical DHEA cream is an effective way to safely increase DHEA levels in adults. Read more here.
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Tivesten A et al. J Am Coll Cardiol. 2014; doi: 10.1016/j.jacc.2014.05.076
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