
The Health Benefits of Nicotine
Nicotine is a nutrients and it is NOT addictive or carcinogenic.
Contrary to what we have been told nicotine is not addictive, it is not a carcinogen and it is IN FACT a nutrient found in many plants including tobacco and some vegetables that we eat. Nicotine is found in the nightshade vegetables, but instead of avoiding these vegetables if you have joint and pain, it has been found that nicotine in these foods have more anti-inflammatory effects than inflammatory effects.
Nicotine content of Vegetables
Benefits
Below I share some studies on the benefits of nicotine and at the end you will find three videos that I encourage you to watch. Dr. Bryan Ardis is the expert on the subject and will show you how this nutrient is beneficial.
To be clear, avoid smoking cigarettes and cigars and vaping. These products created by Big Tobacco contain a boatload of chemicals that ARE addicting and carcinogenic.
To get the benefits you will want to use a nicotine patch. I will show you which one I use.
A quick summary of benefits with details and scientific papers supporting these benefits in the videos linked at the end of this post.
- Anti-inflammatory – benefits for ulcerative colitis, arthritis, sepsis, endotoxemia, and any inflammatory condition.
- Reduces episodes of violent behavior and aggression in people with autism.
- Improves sleep
- Reduces type 1 diabetes and helps with insulin while having a protective effect on pancreatic cells
- Can help long-covid sufferers in as little as one week
- Improves memory and cognition, with benefits for those with Alzheimer’s and Parkinson’s disease
- Can help alleviate memory problems with hypothyroid conditions
- Reverses addiction and schizophrenia
The Science
Brain, Cognition and Memory
“The present review focused on the reported benefits of nicotine in the brain and summarizes the associated underlying mechanisms. Nicotine administration can improve cognitive impairment in Alzheimer’s disease (AD), and dyskinesia and memory impairment in Parkinson’s disease (PD). In terms of its mechanism of action, nicotine slows the progression of PD by inhibiting Sirtuin 6, a stress-responsive protein deacetylase, thereby decreasing neuronal apoptosis and improving neuronal survival. In AD, nicotine improves cognitive impairment by enhancing protein kinase B (also referred to as Akt) activity and stimulating phosphoinositide 3-kinase/Akt signaling, which regulates learning and memory processes.
“Nicotine may also activate thyroid receptor signaling pathways to improve memory impairment caused by hypothyroidism. In healthy individuals, nicotine improves memory impairment caused by sleep deprivation by enhancing the phosphorylation of calmodulin-dependent protein kinase II, an essential regulator of cell proliferation and synaptic plasticity. Furthermore, nicotine may improve memory function through its effect on chromatin modification via the inhibition of histone deacetylases, which causes transcriptional changes in memory-related genes. Finally, nicotine administration has been demonstrated to rescue long-term potentiation in individuals with sleep deprivation, AD, chronic stress and hypothyroidism, primarily by desensitizing α7 nicotinic acetylcholine receptors. To conclude, nicotine has several cognitive benefits in healthy individuals, as well as in those with cognitive dysfunction associated with various diseases.”[source]
Long-haul Covid symptoms reversed within one week with nicotine patches.
Long-haul Covid patients experienced miraculous recovery from symptoms within six days using 7mg Nicotine patches. “Based on the results of this case study, this treatment option—using nicotine patches to combat long-haul COVID—seems far superior to the time-consuming, often underwhelming or disappointing, costly and complex rehabilitation measures currently available to these patients.” [source]
Nicotine reverses hypofrontality in animal models of addiction and schizophrenia
Chronic nicotine administration reversed this hypofrontality, suggesting that administration of nicotine may represent a therapeutic strategy for the treatment of schizophrenia, and a physiological basis for the tendency of patients with schizophrenia to self-medicate by smoking. [source]
Nicotine ameliorates schizophrenia-like cognitive deficits induced by maternal LPS exposure: a study in rats [source]
Transdermal nicotine in non-smokers: A systematic review to design COVID-19 clinical trials [source]
In non-smokers, the use of nicotine transdermal patches has been assessed to treat
- Alzheimer’s-related diseases and cognitive disorders in the elderly and post-cancer chemotherapy [11], [12], [13], [14], [15], [16], [17]
- Autism [18]
- Attention-Deficit Hyperactivity Disorder (ADHD) [19], [20]
- Major depressive disorder [21], [22], [23]
- Parkinson’s disease [24], [25], [26], [27], [28], [29]
- Tourette syndrome [30], [31], [32], [33]
- Ulcerative colitis [34], [35], [36], [37], [38], [39], [40], [41], [42].
- Inflammation [45]
Which Brand of Nicotine Patches is Best?


Nicotine in Inflammatory Diseases: Anti-Inflammatory and Pro-Inflammatory Effects
This study reviewed the anti-inflammatory and pro-inflammatory effects of nicotine on inflammatory diseases, including inflammatory bowel disease, ulcerative colitis, arthritis, periodontitis, sepsis, endotoxemia, multiple sclerosis (MS), nasal eosinophilic inflammation, allergy, nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, skin inflammation, placental inflammation, pancreatitis, Behçet’s disease, muscle inflammation, viral myocarditis, uveitis, experimental autoimmune encephalomyelitis, systemic lupus erythematosus, and so on.
Nicotine could directly affect mitochondrial respiration, cell autophagy, and cell signaling molecules in an environment with proper pH. [source]
An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder
This study provides evidence for the feasibility and tolerability of transdermal nicotine in a small sample of adults with severe Autism Spectrum Disorder symptoms and pathological chronic aggression and irritability. The benefits of nicotine when applied during waking hours reduced aggression and improved sleep quality. [source]
Nicotine reduces the incidence of type I diabetes in mice
Nicotine has been previously shown to have immunosuppressive actions. Type I diabetes is an autoimmune disease resulting from the specific destruction of the insulin-producing pancreatic beta-cells. Thus, we hypothesized that nicotine may exert protective effects against type I diabetes.
Nicotine treatment reduced the hyperglycemia and incidence of disease in both the MLDS and NOD mouse models of diabetes. Nicotine also protected against the diabetes-induced decrease in pancreatic insulin content observed in both animal models. [source]
Further Education on the Benefits of Nicotine
- Video: Nicotine – Dr. Ardis – with Man in America
- Video: The Other N Word (Nicotine) with Bryan Ardis
- Video Truth About Nicotine
How to Start Using Nicotine for Health Benefits
- Day 1 to 14 – apply one 7mg nicotine patch per day
- After day 14 – Cut the patch in half to apply 3.5mg nicotine ongoing.
Nicotine is not addictive. Some people use the patch for 14 days, then take a break for a few days.
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